

Destroy All Humans!
Can your GPU run this game?
Estimated FPS across quality settings and resolutions
Search for your GPU above to see a full FPS breakdown at every quality and resolution.
Destroy All Humans! FPS by GPU
Estimated framerates for 14 reference GPUs · pick a resolution and quality
Full benchmark grid · 14 GPUs × 4 qualities × 3 resolutions
1080p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 788 fps | 630 fps | 504 fps | 410 fps |
| RTX 4090 | 731 fps | 585 fps | 468 fps | 380 fps |
| RX 7900 XTX | 656 fps | 525 fps | 420 fps | 341 fps |
| RTX 5080 | 619 fps | 495 fps | 396 fps | 322 fps |
| RTX 4080 Super | 581 fps | 465 fps | 372 fps | 302 fps |
| RTX 4070 Ti | 459 fps | 368 fps | 294 fps | 239 fps |
| RTX 4070 | 394 fps | 315 fps | 252 fps | 205 fps |
| RX 7800 XT | 347 fps | 278 fps | 222 fps | 180 fps |
| RTX 3080 | 338 fps | 270 fps | 216 fps | 176 fps |
| RTX 4060 Ti | 319 fps | 255 fps | 204 fps | 166 fps |
| RTX 3070 | 291 fps | 233 fps | 186 fps | 151 fps |
| RTX 4060 | 263 fps | 210 fps | 168 fps | 137 fps |
| RTX 3060 | 225 fps | 180 fps | 144 fps | 117 fps |
| GTX 1660 Super | 163 fps | 131 fps | 104 fps | 85 fps |
1440p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 591 fps | 473 fps | 378 fps | 307 fps |
| RTX 4090 | 548 fps | 439 fps | 351 fps | 285 fps |
| RX 7900 XTX | 492 fps | 394 fps | 315 fps | 256 fps |
| RTX 5080 | 464 fps | 371 fps | 297 fps | 241 fps |
| RTX 4080 Super | 436 fps | 349 fps | 279 fps | 227 fps |
| RTX 4070 Ti | 345 fps | 276 fps | 221 fps | 179 fps |
| RTX 4070 | 295 fps | 236 fps | 189 fps | 154 fps |
| RX 7800 XT | 260 fps | 208 fps | 167 fps | 135 fps |
| RTX 3080 | 253 fps | 203 fps | 162 fps | 132 fps |
| RTX 4060 Ti | 239 fps | 191 fps | 153 fps | 124 fps |
| RTX 3070 | 218 fps | 174 fps | 140 fps | 113 fps |
| RTX 4060 | 197 fps | 158 fps | 126 fps | 102 fps |
| RTX 3060 | 169 fps | 135 fps | 108 fps | 88 fps |
| GTX 1660 Super | 122 fps | 98 fps | 78 fps | 64 fps |
4K performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 315 fps | 252 fps | 202 fps | 164 fps |
| RTX 4090 | 293 fps | 234 fps | 187 fps | 152 fps |
| RX 7900 XTX | 263 fps | 210 fps | 168 fps | 137 fps |
| RTX 5080 | 248 fps | 198 fps | 158 fps | 129 fps |
| RTX 4080 Super | 233 fps | 186 fps | 149 fps | 121 fps |
| RTX 4070 Ti | 184 fps | 147 fps | 118 fps | 96 fps |
| RTX 4070 | 158 fps | 126 fps | 101 fps | 82 fps |
| RX 7800 XT | 139 fps | 111 fps | 89 fps | 72 fps |
| RTX 3080 | 135 fps | 108 fps | 86 fps | 70 fps |
| RTX 4060 Ti | 128 fps | 102 fps | 82 fps | 66 fps |
| RTX 3070 | 116 fps | 93 fps | 74 fps | 60 fps |
| RTX 4060 | 105 fps | 84 fps | 67 fps | 55 fps |
| RTX 3060 | 90 fps | 72 fps | 58 fps | 47 fps |
| GTX 1660 Super | 65 fps | 52 fps | 42 fps | 34 fps |

Where to buy
Destroy All Humans!
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Minimum Hardware
AMD/NVIDIA dedicated graphics card, with at least 4GB of dedicated VRAM and with at least DirectX 11.0 and Shader Model 5.1 support
AMD / Intel CPU running at 3.0 GHz or higher: AMD Kaveri A10-7850K or Intel Pentium DualCore G3220 or newer is recommended / Ryzen 5 2400G (for systems using an integrated GPU)
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About
To run Destroy All Humans! smoothly, an entry-level GPU like the GTX 1650 or RX 6500 XT should suffice. Given that the game was released in 2005, it is not particularly demanding and is accessible to a wide range of hardware. Players with these GPUs can expect to enjoy the game at 1080p resolution with high settings while maintaining good frame rates.
For those using more powerful GPUs, such as the GTX 1660 or RX 580, 1440p resolution is achievable with similar high settings. Even older GPUs from that era, like the GTX 960, can manage decent performance at lower settings. Overall, the game is easy to run on modest hardware, making it a great pick for casual gamers or those revisiting classic titles. Consider your GPU capabilities, and you'll likely have a fantastic experience without the need for high-end components.
Performance profile
Released in December 2005, Destroy All Humans! comes from the DirectX 9 era. Even the cheapest modern discrete GPU crushes it at maxed-out settings; the only real bottleneck today is CPU single-thread speed on older titles that were never multi-threaded.
Entry-level hardware target. A GTX 1650 or RX 6500 XT reaches 60 FPS at 1080p Medium in Destroy All Humans!; an RTX 4060 comfortably sustains 1440p Ultra. 4K Ultra 60 FPS needs an RTX 4070 or better.