Plague Doctor and Panacea
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Estimated FPS across quality settings and resolutions
Search for your GPU above to see a full FPS breakdown at every quality and resolution.
Plague Doctor and Panacea FPS by GPU
Estimated framerates for 14 reference GPUs · pick a resolution and quality
Full benchmark grid · 14 GPUs × 4 qualities × 3 resolutions
1080p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 999 fps | 940 fps | 752 fps | 611 fps |
| RTX 4090 | 999 fps | 872 fps | 698 fps | 567 fps |
| RX 7900 XTX | 979 fps | 783 fps | 626 fps | 509 fps |
| RTX 5080 | 923 fps | 738 fps | 591 fps | 480 fps |
| RTX 4080 Super | 867 fps | 694 fps | 555 fps | 451 fps |
| RTX 4070 Ti | 685 fps | 548 fps | 438 fps | 356 fps |
| RTX 4070 | 587 fps | 470 fps | 376 fps | 305 fps |
| RX 7800 XT | 517 fps | 414 fps | 331 fps | 269 fps |
| RTX 3080 | 503 fps | 403 fps | 322 fps | 262 fps |
| RTX 4060 Ti | 475 fps | 380 fps | 304 fps | 247 fps |
| RTX 3070 | 433 fps | 347 fps | 277 fps | 225 fps |
| RTX 4060 | 391 fps | 313 fps | 251 fps | 204 fps |
| RTX 3060 | 336 fps | 268 fps | 215 fps | 174 fps |
| GTX 1660 Super | 243 fps | 195 fps | 156 fps | 127 fps |
1440p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 881 fps | 705 fps | 564 fps | 458 fps |
| RTX 4090 | 818 fps | 654 fps | 523 fps | 425 fps |
| RX 7900 XTX | 734 fps | 587 fps | 470 fps | 382 fps |
| RTX 5080 | 692 fps | 554 fps | 443 fps | 360 fps |
| RTX 4080 Super | 650 fps | 520 fps | 416 fps | 338 fps |
| RTX 4070 Ti | 514 fps | 411 fps | 329 fps | 267 fps |
| RTX 4070 | 440 fps | 352 fps | 282 fps | 229 fps |
| RX 7800 XT | 388 fps | 310 fps | 248 fps | 202 fps |
| RTX 3080 | 378 fps | 302 fps | 242 fps | 196 fps |
| RTX 4060 Ti | 357 fps | 285 fps | 228 fps | 185 fps |
| RTX 3070 | 325 fps | 260 fps | 208 fps | 169 fps |
| RTX 4060 | 294 fps | 235 fps | 188 fps | 153 fps |
| RTX 3060 | 252 fps | 201 fps | 161 fps | 131 fps |
| GTX 1660 Super | 182 fps | 146 fps | 117 fps | 95 fps |
4K performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 470 fps | 376 fps | 301 fps | 244 fps |
| RTX 4090 | 436 fps | 349 fps | 279 fps | 227 fps |
| RX 7900 XTX | 391 fps | 313 fps | 251 fps | 204 fps |
| RTX 5080 | 369 fps | 295 fps | 236 fps | 192 fps |
| RTX 4080 Super | 347 fps | 277 fps | 222 fps | 180 fps |
| RTX 4070 Ti | 274 fps | 219 fps | 175 fps | 143 fps |
| RTX 4070 | 235 fps | 188 fps | 150 fps | 122 fps |
| RX 7800 XT | 207 fps | 166 fps | 132 fps | 108 fps |
| RTX 3080 | 201 fps | 161 fps | 129 fps | 105 fps |
| RTX 4060 Ti | 190 fps | 152 fps | 122 fps | 99 fps |
| RTX 3070 | 173 fps | 139 fps | 111 fps | 90 fps |
| RTX 4060 | 157 fps | 125 fps | 100 fps | 81 fps |
| RTX 3060 | 134 fps | 107 fps | 86 fps | 70 fps |
| GTX 1660 Super | 97 fps | 78 fps | 62 fps | 51 fps |
Where to buy
Plague Doctor and Panacea
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Minimum Hardware
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Genres
About
For "Plague Doctor and Panacea," an entry-level GPU like the GTX 1650 or RX 6500 XT should handle the game comfortably at 1080p with medium settings. This combination will provide a smooth experience, allowing players to immerse themselves in the game's atmospheric environments without major frame rate drops. If you're aiming for higher fidelity, such as 1440p, consider a more robust GPU like the GTX 1660 Super or RTX 2060 to maintain solid performance.
The game is designed to be accessible, meaning that even lower-tier systems can enjoy it without significant sacrifices in quality. Players with mid-range setups can expect to push settings to high while still achieving good frame rates, making it suitable for a wide range of hardware. Overall, for the best experience, aim for at least a GTX 1660 or RX 6600 if you wish to enjoy higher settings and resolutions without compromising performance.
Performance profile
February 2025 release. As a current-generation title, Plague Doctor and Panacea pushes modern hardware — expect to need an RTX 40-series or RX 7000-series GPU to enjoy it at native 4K Ultra without leaning on upscaling.
Simulation titles like Plague Doctor and Panacea are heavily CPU-dependent — physics, AI and world state dominate the frame budget. Prioritise a CPU with strong single-thread performance and fast RAM over raw GPU power.
Entry-level hardware target. A GTX 1650 or RX 6500 XT reaches 60 FPS at 1080p Medium in Plague Doctor and Panacea; an RTX 4060 comfortably sustains 1440p Ultra. 4K Ultra 60 FPS needs an RTX 4070 or better.
