Plague M.D.
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Estimated FPS across quality settings and resolutions
Search for your GPU above to see a full FPS breakdown at every quality and resolution.
Plague M.D. FPS by GPU
Estimated framerates for 14 reference GPUs · pick a resolution and quality
Full benchmark grid · 14 GPUs × 4 qualities × 3 resolutions
1080p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4090 | 999 fps | 999 fps | 999 fps | 999 fps |
| RX 7900 XTX | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 5080 | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4080 Super | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4070 Ti | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4070 | 999 fps | 999 fps | 999 fps | 999 fps |
| RX 7800 XT | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 3080 | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4060 Ti | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 3070 | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4060 | 999 fps | 999 fps | 999 fps | 970 fps |
| RTX 3060 | 999 fps | 999 fps | 999 fps | 831 fps |
| GTX 1660 Super | 999 fps | 927 fps | 742 fps | 603 fps |
1440p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4090 | 999 fps | 999 fps | 999 fps | 999 fps |
| RX 7900 XTX | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 5080 | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4080 Super | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4070 Ti | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4070 | 999 fps | 999 fps | 999 fps | 999 fps |
| RX 7800 XT | 999 fps | 999 fps | 999 fps | 961 fps |
| RTX 3080 | 999 fps | 999 fps | 999 fps | 935 fps |
| RTX 4060 Ti | 999 fps | 999 fps | 999 fps | 883 fps |
| RTX 3070 | 999 fps | 999 fps | 991 fps | 805 fps |
| RTX 4060 | 999 fps | 999 fps | 895 fps | 727 fps |
| RTX 3060 | 999 fps | 959 fps | 767 fps | 623 fps |
| GTX 1660 Super | 869 fps | 695 fps | 556 fps | 452 fps |
4K performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 999 fps | 999 fps | 999 fps | 999 fps |
| RTX 4090 | 999 fps | 999 fps | 999 fps | 999 fps |
| RX 7900 XTX | 999 fps | 999 fps | 999 fps | 970 fps |
| RTX 5080 | 999 fps | 999 fps | 999 fps | 914 fps |
| RTX 4080 Super | 999 fps | 999 fps | 999 fps | 859 fps |
| RTX 4070 Ti | 999 fps | 999 fps | 836 fps | 679 fps |
| RTX 4070 | 999 fps | 895 fps | 716 fps | 582 fps |
| RX 7800 XT | 986 fps | 789 fps | 631 fps | 513 fps |
| RTX 3080 | 959 fps | 767 fps | 614 fps | 499 fps |
| RTX 4060 Ti | 906 fps | 725 fps | 580 fps | 471 fps |
| RTX 3070 | 826 fps | 661 fps | 529 fps | 429 fps |
| RTX 4060 | 746 fps | 597 fps | 477 fps | 388 fps |
| RTX 3060 | 639 fps | 512 fps | 409 fps | 333 fps |
| GTX 1660 Super | 464 fps | 371 fps | 297 fps | 241 fps |
Where to buy
Plague M.D.
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$5.99
$4.79
-20% off
Minimum Hardware
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Genres
About
To run Plague M.D. smoothly, an entry-level GPU like the GTX 1650 or RX 6500 XT is sufficient for basic gameplay. Given its indie status and design, the game is not very demanding, making it accessible for a wide range of systems. Players with these GPUs can expect decent performance at 1080p resolution on medium settings, which will provide a satisfactory visual experience without straining the hardware.
For those with older or less powerful systems, the game can still be enjoyed with integrated graphics or older GPUs, but you may need to lower your resolution to 720p and set graphics to low to maintain a playable frame rate. Overall, Plague M.D. is a great option for casual gamers looking for a unique simulation experience without the need for high-end specifications. If you're looking for something light and engaging, this title will fit well within the capabilities of most modern PCs.
Performance profile
Released in September 2020, Plague M.D. targets RTX 20/30-series and RX 6000-era hardware. A current mid-range GPU (RTX 4060 Ti / RX 7700 XT) is the sweet spot for 1440p Ultra; 4K needs a high-end card.
Simulation titles like Plague M.D. are heavily CPU-dependent — physics, AI and world state dominate the frame budget. Prioritise a CPU with strong single-thread performance and fast RAM over raw GPU power.
Extremely light — Plague M.D. runs at 60 FPS 1080p on any integrated GPU (Intel Iris Xe, AMD Radeon Graphics) or a decade-old discrete card like the GTX 1050. A current-gen RTX 4060 pushes 4K Ultra without effort.
Storyline
Become a quack doctor stuck in a backwater village in the 16th century. The illnesses of the peasants are varied: neighbor's kid always covered in bruises, the blacksmith complains about his sight, and the priest has stopped praying at all and does not leave the house. Well, what can you do? At first, your methods are scarce - drain blood, amputate a rotten finger. But over time, you become increasingly sophisticated, learning therapeutic treatments and surgical skills. Eventually, you face the horror of black death and put on a plague doctor mask.
