Prescription: Madness
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Estimated FPS across quality settings and resolutions
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Prescription: Madness FPS by GPU
Estimated framerates for 14 reference GPUs · pick a resolution and quality
Full benchmark grid · 14 GPUs × 4 qualities × 3 resolutions
1080p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 954 fps | 763 fps | 611 fps | 496 fps |
| RTX 4090 | 886 fps | 709 fps | 567 fps | 461 fps |
| RX 7900 XTX | 795 fps | 636 fps | 509 fps | 413 fps |
| RTX 5080 | 750 fps | 600 fps | 480 fps | 390 fps |
| RTX 4080 Super | 704 fps | 563 fps | 451 fps | 366 fps |
| RTX 4070 Ti | 556 fps | 445 fps | 356 fps | 289 fps |
| RTX 4070 | 477 fps | 382 fps | 305 fps | 248 fps |
| RX 7800 XT | 420 fps | 336 fps | 269 fps | 219 fps |
| RTX 3080 | 409 fps | 327 fps | 262 fps | 213 fps |
| RTX 4060 Ti | 386 fps | 309 fps | 247 fps | 201 fps |
| RTX 3070 | 352 fps | 282 fps | 225 fps | 183 fps |
| RTX 4060 | 318 fps | 254 fps | 204 fps | 165 fps |
| RTX 3060 | 273 fps | 218 fps | 174 fps | 142 fps |
| GTX 1660 Super | 198 fps | 158 fps | 126 fps | 103 fps |
1440p performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 715 fps | 572 fps | 458 fps | 372 fps |
| RTX 4090 | 664 fps | 531 fps | 425 fps | 345 fps |
| RX 7900 XTX | 596 fps | 477 fps | 382 fps | 310 fps |
| RTX 5080 | 562 fps | 450 fps | 360 fps | 292 fps |
| RTX 4080 Super | 528 fps | 422 fps | 338 fps | 275 fps |
| RTX 4070 Ti | 417 fps | 334 fps | 267 fps | 217 fps |
| RTX 4070 | 358 fps | 286 fps | 229 fps | 186 fps |
| RX 7800 XT | 315 fps | 252 fps | 202 fps | 164 fps |
| RTX 3080 | 307 fps | 245 fps | 196 fps | 159 fps |
| RTX 4060 Ti | 290 fps | 232 fps | 185 fps | 151 fps |
| RTX 3070 | 264 fps | 211 fps | 169 fps | 137 fps |
| RTX 4060 | 238 fps | 191 fps | 153 fps | 124 fps |
| RTX 3060 | 204 fps | 164 fps | 131 fps | 106 fps |
| GTX 1660 Super | 148 fps | 119 fps | 95 fps | 77 fps |
4K performance
| GPU | low | medium | high | ultra |
|---|---|---|---|---|
| RTX 5090 | 382 fps | 305 fps | 244 fps | 198 fps |
| RTX 4090 | 354 fps | 283 fps | 227 fps | 184 fps |
| RX 7900 XTX | 318 fps | 254 fps | 204 fps | 165 fps |
| RTX 5080 | 300 fps | 240 fps | 192 fps | 156 fps |
| RTX 4080 Super | 282 fps | 225 fps | 180 fps | 146 fps |
| RTX 4070 Ti | 223 fps | 178 fps | 142 fps | 116 fps |
| RTX 4070 | 191 fps | 153 fps | 122 fps | 99 fps |
| RX 7800 XT | 168 fps | 134 fps | 108 fps | 87 fps |
| RTX 3080 | 164 fps | 131 fps | 105 fps | 85 fps |
| RTX 4060 Ti | 154 fps | 124 fps | 99 fps | 80 fps |
| RTX 3070 | 141 fps | 113 fps | 90 fps | 73 fps |
| RTX 4060 | 127 fps | 102 fps | 81 fps | 66 fps |
| RTX 3060 | 109 fps | 87 fps | 70 fps | 57 fps |
| GTX 1660 Super | 79 fps | 63 fps | 51 fps | 41 fps |
Where to buy
Prescription: Madness
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Minimum Hardware
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Genres
About
To run this visual novel smoothly, an entry-level GPU like the GTX 1650 or RX 6500 XT is sufficient for the minimum requirements. This means players with budget-friendly setups can enjoy the game without significant performance issues. However, for a better experience, particularly at higher resolutions or improved visual settings, a mid-range GPU such as the GTX 1660 or RX 6600 would be recommended.
At 1080p resolution, players with the minimum GPU should aim for low to medium settings to maintain a stable frame rate, while those with mid-tier hardware can comfortably push the settings to high without sacrificing performance. The game is not particularly demanding, making it accessible for a wide range of systems. Overall, it's a solid choice for casual gamers looking for an engaging narrative without the need for top-tier hardware.
Performance profile
March 2026 release. As a current-generation title, Prescription: Madness pushes modern hardware — expect to need an RTX 40-series or RX 7000-series GPU to enjoy it at native 4K Ultra without leaning on upscaling.
Simulation titles like Prescription: Madness are heavily CPU-dependent — physics, AI and world state dominate the frame budget. Prioritise a CPU with strong single-thread performance and fast RAM over raw GPU power.
Entry-level hardware target. A GTX 1650 or RX 6500 XT reaches 60 FPS at 1080p Medium in Prescription: Madness; an RTX 4060 comfortably sustains 1440p Ultra. 4K Ultra 60 FPS needs an RTX 4070 or better.
Storyline
What does it feel like to be a sentient body part that's attached to another being? Welcome to the Netherworld, where you play as a sentient tentacle of the great master Cthulhu. What happens when a sentient tentacle, wants to find its own purpose? Like get a job? Or rid the world of humanity? Or play doctor at hospital in the Overworld? How would that... work? You’re a snarky sentient tentacle in a chaotic hospital. Possess humans and creatures, befriend the right weirdos, and decide humanity’s fate in this dark humor visual novel where every character is a potential pawn… or pal.
